• Antitumor activities and cellular changes induced by TrkB inhibition in medulloblastoma 

      Thomaz, Amanda Cristina Godot; Pinheiro, Kelly de Vargas; Souza, Bárbara Kunzler; Gregianin, Lauro José; Brunetto, Algemir Lunardi; Brunetto, Andre Tessainer; Farias, Caroline Brunetto de; Jaeger, Mariane da Cunha; Ramaswamy, Vijay; Nor, Carolina; Taylor, Michael David; Roesler, Rafael (2019) [Artigo de periódico]
      Neurotrophins are critically involved in regulating normal neural development and plasticity. Brain-derived neurotrophic factor (BDNF), a neurotrophin that acts by binding to the tropomyosin receptor kinase B (TrkB) receptor, ...
    • Influence of GRPR and BDNF/TrkB signaling on the viability of breast and gynecologic cancer cells 

      Cornélio, Daniela Baumann; Farias, Caroline Brunetto de; Prusch, Débora Schoenfeld; Heinen, Tiago Elias; Santos, Rafael Pereira dos; Abujamra, Ana Lúcia; Schwartsmann, Gilberto; Roesler, Rafael (2013) [Artigo de periódico]
      Neuropeptide and neurotrophin receptors are increasingly important molecular targets in cancer. Scientific findings indicate that compounds blocking gastrin-releasing peptide receptors (GRPR) or tropomyosin receptor kinase ...