Navegação por Assunto "Transcription factors"
Resultados 1-4 de 4
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Alterações em componentes inibitórios ao longo do neurodesenvolvimento : efeitos preventivos do resveratrol em modelo animal de TEA
(2022) [Tese]O transtorno do espectro autista (TEA) é uma desordem multifatorial complexa cuja fisiopatologia ainda não é completamente compreendida. Entretanto, algumas características, como as alterações nos componentes inibitórios ... -
Alzheimer's disease master regulators analysis : search for potential molecular targets and drug repositioning candidates
(2018) [Artigo de periódico]Background: Alzheimer’s disease (AD) is a multifactorial and complex neuropathology that involves impairment of many intricate molecular mechanisms. Despite recent advances, AD pathophysiological characterization remains ... -
Genome-wide annotation of the soybean WRKY family and functional characterization of genes involved in response to Phakopsora pachyrhizi infection
(2014) [Artigo de periódico]Background: Many previous studies have shown that soybean WRKY transcription factors are involved in the plant response to biotic and abiotic stresses. Phakopsora pachyrhizi is the causal agent of Asian Soybean Rust, one ... -
Master regulators connectivity map : a transcription factors-centered approach to drug repositioning
(2018) [Artigo de periódico]Drug discovery is a very expensive and time-consuming endeavor. Fortunately, recent omics technologies and Systems Biology approaches introduced interesting new tools to achieve this task, facilitating the repurposing of ...