Adiposity markers and risk of coronary heart disease in patients with type 2 diabetes mellitus
dc.contributor.author | Tonding, Simone Frederico | pt_BR |
dc.contributor.author | Silva, Flávia Moraes | pt_BR |
dc.contributor.author | Antonio, Juliana Peçanha | pt_BR |
dc.contributor.author | Azevedo, Mirela Jobim de | pt_BR |
dc.contributor.author | Canani, Luis Henrique Santos | pt_BR |
dc.contributor.author | Almeida, Jussara Carnevale de | pt_BR |
dc.date.accessioned | 2015-03-07T01:57:08Z | pt_BR |
dc.date.issued | 2014 | pt_BR |
dc.identifier.issn | 1475-2891 | pt_BR |
dc.identifier.uri | http://hdl.handle.net/10183/111821 | pt_BR |
dc.description.abstract | Background: This cross-sectional study aimed to evaluating the association between body adiposity markers and high-risk of coronary heart disease (CHD) in patients with type 2 diabetes. Methods: Recent adiposity markers [waist-to-height ratio, conicity index (C-index) and body adiposity index] and traditional markers [BMI, waist circumference and waist-to-hip ratio (WHR)] were measured. The 10-year risk of fatal CHD was estimated according to UKPDS risk engine scores. Patients were divided into high (CHD risk ≥20%; n = 99) or low-moderate (CHD risk <20%; n = 321) risk groups. Multiple logistic regression models were performed to analyze associations between CHD risk (outcome) and adiposity markers. Results: A total of 420 patients with type 2 diabetes (61.9 ± 9.5 years; 53.5% females; HbA1c 7.6 ± 1.6%) were evaluated. The high risk group had greater proportions of elevated C-index and BMI values than patients with low-moderate risk. No between-group differences in other adiposity markers were observed. In multiple logistic regression models, only C-index values ≥1.35 were associated with CHD risk >20% (OR = 1.69; 95% CI 1.03-2.78; P = 0.039) after adjusting for confounders (sedentary lifestyle, diabetic nephropathy, serum creatinine, and diabetes duration). The association between WHR and CHD risk did not hold in this sample. Conclusions: The C-index was the body adiposity marker best associated with high risk of fatal CHD in these patients with type 2 diabetes. | en |
dc.format.mimetype | application/pdf | |
dc.language.iso | eng | pt_BR |
dc.relation.ispartof | Nutrition journal. London. Vol. 13 (Dec. 2014), 7p. | pt_BR |
dc.rights | Open Access | en |
dc.subject | Anthropometry | en |
dc.subject | Antropometria | pt_BR |
dc.subject | Body fat distribution | en |
dc.subject | Distribuição da gordura corporal | pt_BR |
dc.subject | Obesidade abdominal | pt_BR |
dc.subject | Obesity abdominal | en |
dc.subject | Coronary disease | en |
dc.subject | Doença das coronárias | pt_BR |
dc.subject | Diabetes mellitus tipo 2 | pt_BR |
dc.subject | Diabetes mellitus type 2 | en |
dc.title | Adiposity markers and risk of coronary heart disease in patients with type 2 diabetes mellitus | pt_BR |
dc.type | Artigo de periódico | pt_BR |
dc.identifier.nrb | 000953059 | pt_BR |
dc.type.origin | Estrangeiro | pt_BR |
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