Navegação Ciências Biológicas por Assunto "5'-nucleotidase"
Resultados 1-6 de 6
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Brain ischemia alters platelet ATP disphosphohydrolase and 5'-nucleotidase activities in naive and preconditioned rats
(2000) [Artigo de periódico]The effects of transient forebrain ischemia, reperfusion and ischemic preconditioning on rat blood platelet ATP diphosphohydrolase and 5'- nucleotidase activities were evaluated. Adult Wistar rats were submitted to 2 or ... -
CD39 and CD73 as promising therapeutic targets : what could be the limitations?
(2021) [Artigo de periódico] -
Characterization of ectonucleotidases in human medulloblastoma cell lines : ecto-5´NT/CD73 in metastasis as potential prognostic factor
(2012) [Artigo de periódico]Medulloblastoma (MB) is the most common malignant brain tumor in children and occurs mainly in the cerebellum. Important intracellular signaling molecules, such those present in the Sonic Hedgehog and Wnt pathways, are ... -
Differential macrophage activation alters the expression profile of NTPDase and Ecto-5´-nucleotidase
(2012) [Artigo de periódico]Macrophages are key elements in the inflammatory process, whereas depending on the micro-environmental stimulation they exhibit a pro-inflammatory (classical/M1) or an anti-inflammatory/reparatory (alternative/M2) phenotype. ... -
Dysfunctional purinergic signaling correlates with disease severity in COVID-19 patients
(2022) [Artigo de periódico]Ectonucleotidases modulate inflammatory responses by balancing extracellular ATP and adenosine (ADO) and might be involved in COVID-19 immunopathogenesis. Here, we explored the contribution of extracellular nucleotide ... -
Morphine treatment alters nucleotidase activities in rat blood serum
(2012) [Artigo de periódico]Morphine has been widely used in neonatal pain management. However, this treatment may produce adaptive changes in several physiologic systems. Our laboratory has demonstrated that morphine treatment in neonate rats alters ...