Navegação Ciências Biológicas por Assunto "Expressão gênica"
Resultados 1-18 de 18
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Altered expression of COX-2 and TNF-α in patients with hepatocellular carcinoma
(2019) [Artigo de periódico]Background and aim: hepatocellular carcinoma is a type of cancer related with inflammation, as 90% of cases develop in a chronic inflammation condition. Excess inflammation can affect tissue homeostasis. Cytokines and ... -
Analysis of the cancer genome atlas data reveals novel putative ncRNAs targets in hepatocellular carcinoma
(2018) [Artigo de periódico]Hepatocellular carcinoma (HCC) is the prevalent type of primary liver malignancy. Different noncoding RNAs (ncRNAs) that negatively regulate gene expression, such as the microRNAs and the long ncRNAs (lncRNAs), have been ... -
Androgen receptor isoforms expression in benign prostatic hyperplasia and primary prostate cancer
(2018) [Artigo de periódico]The role of molecular changes in the androgen receptor (AR) as AR variants (AR-Vs) is not clear in the pathophysiology of benign prostatic hyperplasia (BPH) and hormone-naïve PCa. The aim of the current work was to identify ... -
Avaliação da expressão relativa dos genes envolvidos na formação de biofilme por Acinetobacter baumannii
(2018) [Artigo de periódico]Acinetobacter baumannii é um patógeno oportunista, de grande importância no ambiente hospitalar devido à sua capacidade de adquirir mecanismos de resistência, de aderir e formar biofilmes sob diferentes superfícies. Devido ... -
Cognitive development and brain gray matter susceptibility to prenatal adversities : moderation by the prefrontal cortex brain-derived neurotrophic factor gene co-expression network
(2021) [Artigo de periódico]Background: Previous studies focused on the relationship between prenatal conditions and neurodevelopmental outcomes later in life, but few have explored the interplay between gene co-expression networks and prenatal ... -
Differential expression of transcriptional regulatory units in the prefrontal cortex of patients with bipolar disorder : potential role of early growth response gene 3
(2016) [Artigo de periódico]Bipolar disorder (BD) is a severe mental illness with a strong genetic component. Despite its high degree of heritability, current genetic studies have failed to reveal individual loci of large effect size. In lieu of ... -
Effect of Helicobacter pylori on NFKB1, p38α and TNF-α mRNA expression levels in human gastric mucosa
(2016) [Artigo de periódico]Helicobacter pylori infects ~50% of the world population, causing chronic gastritis and other forms of cellular damage. The present study assessed the influence of H. pylori on the mRNA expression levels of nuclear factor ... -
Effects of short-term arsenic exposure in Arabidopsis thaliana : tolerance versus toxicity responses
(2019) [Artigo de periódico]The metalloid arsenic (As) is highly phytotoxic, in part due to the similarity of the arsenates to phosphates, but also due to its ability to induce reactive oxygen species (ROS) formation, and in the form of arsenite ... -
Expressão gênica das células do cumulus oophorus de bovinos após vitrificação
(2010) [Artigo de periódico]Um dos desafios da criobiologia continua sendo o desenvolvimento de um método que proporcione a manutenção da viabilidade após a criopreservação de oócitos imaturos na espécie bovina. A vitrificação tem sido a metodologia ... -
Gene expression and in vitro nuclear maturation in bovine cumulus oocyte complexes maturated in a medium supplemented with bovine fetal serum or bovine serum albumin
(2013) [Artigo de periódico]Background: The expansion and mucifi cation of granulosa cells of the cumulus oophorus-oocyte complex (COC) is observed during the oocyte in vitro maturation (IVM) as a result of the intense synthesis of extracellular ... -
Gene expression changes associated with chemotherapy resistance in Ewing sarcoma cells
(2018) [Artigo de periódico]Ewing Sarcoma (ES) is a highly aggressive bone and soft tissue childhood cancer. The development of resistance to chemotherapy is common and remains the main cause of treatment failure. We herein evaluated the expression ... -
Global analysis of sRNA target genes in Mycoplasma hyopneumoniae
(2018) [Artigo de periódico]Background: Small RNAs (sRNAs) are noncoding molecules that regulate different cellular activities in several bacteria. The role of sRNAs in gene expression regulation is poorly characterized in the etiological agent of ... -
Interaction of HSD11B1 and H6PD polymorphisms in subjects with type 2 diabetes are protective factors against obesity : a cross-sectional study
(2019) [Artigo de periódico]Background: The enzyme 11-beta hydroxysteroid dehydrogenase type 1 (HSD11B1) converts inactive cortisone to active cortisol in a process mediated by the enzyme hexose-6-phosphate dehydrogenase (H6PD). The generation of ... -
Modulation of gene expression by essential oils in bacteria
(2018) [Artigo de periódico]The emerging of drug-resistant strains imposes some new strategies in prevent bacteria spread. It is pivotal to find new candidates for drug development. The essential oils (EOs) extracted from plants are alternatives for ... -
Molecular mechanisms of Zika virus teratogenesis from animal studies : a systematic review protocol
(2021) [Artigo de periódico]Background: Due to the diversity of studies in animal models reporting that molecular mechanisms are involved in the teratogenic effect of the Zika virus (ZIKV), the objective of the present study is to evaluate the ... -
MSX1 and PAX9 investigation in monozygotic twins with variable expression of tooth agenesis
(2013) [Artigo de periódico]Non-syndromic agenesis of permanent teeth is one of the most common anomalies in human development, a multifactorial characteristic caused by genetic and environmental factors. We describe a pair of monozygotic twins who ... -
Oxidative stress enhances the expression of sulfur assimilation genes: preliminary insights on the Enterococcus faecalis iron-sulfur cluster machinery regulation
(2014) [Artigo de periódico]The Firmicutes bacteria participate extensively in virulence and pathological processes. Enterococcus faecalis is a commensal microorganism; however, it is also a pathogenic bacterium mainly associated with nosocomial ... -
Validation of reference genes for normalization gene expression in reverse transcription quantitative PCR in human normal thyroid and goiter tissue
(2014) [Artigo de periódico]Alternaria sp. MG1, an endophytic fungus isolated from Vitis vinifera, can independently produce resveratrol, indicating that this species contains the key genes for resveratrol biosynthesis. Identification of these key ...