Navegação Ciências Biológicas por Assunto "Zika virus"

Resultados 1-14 de 14

    • Association between Genetic Variants in NOS2 and TNF Genes with Congenital Zika Syndrome and Severe Microcephaly 

      Gomes, Julia do Amaral; Boquett, Juliano André; Silva, Juliana Herrero da; Galera, Marcial Francis; Andrade, Maria Denise Fernandes Carvalho de; Carvalho, Isabella Fernandes; Vianna, Fernanda Sales Luiz; Sgarioni, Eduarda; Trettel, Ana Cláudia Pereira Terças; Ribeiro, Bethânia de Freitas Rodrigues; Oliveira, Thalita Mara de; Faccini, Lavinia Schuler (2021) [Artigo de periódico]
      Zika virus (ZIKV) causes Congenital Zika Syndrome (CZS) in individuals exposed prenatally. Here, we investigated polymorphisms in VEGFA, PTGS2, NOS3, TNF, and NOS2 genes as risk factors to CZS. Forty children with CZS and ...

    • Avaliação da toxicidade pré-natal : estudo de teratogenicidade do inseticida piriproxifeno em ratos Wistar 

      Sartori, Amanda S.; Hollenbach, Clarissa Boemler; Jardim, Lais Hartmann; Silva, Priscila Ramires da; Mello, Fernanda Bastos de; Mello, Joao Roberto Braga de (2020) [Artigo de periódico]
      Este estudo investigou a toxicidade pré-natal do inseticida piriproxifeno em ratos Wistar, de forma a detectar possíveis alterações no desenvolvimento fetal da progênie exposta durante o período organogênico. Três doses ...

    • Classification algorithm for congenital Zika Syndrome: characterizations, diagnosis and validation 

      Veiga, Rafael Valente; Faccini, Lavinia Schuler; França, Giovanny Vinícius Araújo de; Andrade, Roberto Fernandes Silva; Teixeira, Maria Gloria; Costa, Larissa Catharina; Paixão, Enny Santos da; Costa, Maria da Conceição Nascimento; Barreto, Mauricio Lima; Oliveira, Juliane Fonseca de; Oliveira, Wanderson Kleber de; Cardim, Luciana Lobato; Rodrigues, Moreno Magalhães de Souza (2021) [Artigo de periódico]
      Zika virus was responsible for the microcephaly epidemic in Brazil which began in October 2015 and brought great challenges to the scientific community and health professionals in terms of diagnosis and classification. Due ...

    • Epidemiological profile of 39 cases of microcephaly caused by congenital infections diagnosed in the state of Rio Grande do Sul between 2015-2017 

      Herber, Silvani; Terra, Anna Pires; Silva, André Anjos da; Sanseverino, Maria Teresa Vieira; Fraga, Lucas Rosa; Vianna, Fernanda Sales Luiz; Schwartz, Ida Vanessa Doederlein; Faccini, Lavinia Schuler; Friedrich, Luciana (2019) [Artigo de periódico]
      Introduction: Microcephaly is a clinical finding that can arise from congenital anomalies or emerge after childbirth. Maternal infections acquired during pregnancy can result in characteristic brain damage in the newborn ...

    • From abortion-inducing medications to Zika Virus Syndrome : 27 years experience of the First Teratogen Information Service in Latin America 

      Faccini, Lavinia Schuler; Sanseverino, Maria Teresa Vieira; Abeche, Alberto Mantovani; Vianna, Fernanda Sales Luiz; Fraga, Lucas Rosa; Rocha, Anastácia Guimarães; Silva, André Anjos da; Souza, Paulo Ricardo Assis de; Hilgert, Artur Hartmann; Barbosa, Camila Pocharski; Kauppinem, Caroline Grasso; Martins, Daniela Fernandes; Santos, Daniela Silva; Colpes, Gabriel Henrique; Ecco, Gabriela; Silva, Helena Margot Flôres Soares da; Penteado, Louise Piva; Santos, Tatiane dos (2019) [Artigo de periódico]
      In 1990, the first Teratogen Information Service in Brazil (SIAT) was implemented in the Medical Genetics Service at Hospital de Clinicas de Porto Alegre. SIAT is a free-to-use information service both to health professionals ...

    • Knowledge and actions for the control of the vector Aedes aegypti in a municipality in the Legal Amazon 

      Navarro, Jacqueline Pimenta; Martinez Espinosa, Mariano; Trettel, Ana Cláudia Pereira Terças; Silva, Juliana Herrero da; Faccini, Lavinia Schuler; Atanaka, Marina (2021) [Artigo de periódico]
      Infections caused by arboviruses that have mostly impacted the Brazilian morbidity and mortality are caused by the same vector, Aedes aegypti. Preventive actions related to the vector are the most effective strategies in ...

    • Microcephaly prevalence after the 2015 to 2016 Zika outbreak in Tangará da Serra, Brazil: a population-based study 

      Silva, Juliana Herrero da; Trettel, Ana Cláudia Pereira Terças; Boquett, Juliano André; França, Giovanny Vinícius Araújo de; Santos, Augusto César Cardoso dos; Atanaka, Mariana; Oliveira, Marcelo Zagonel de; Terra, Anna Pires; Vivi-Oliveira, Viviane Karolina; Nunes, Lúcia Andréia Nunes de Oliveira; Schaedler, Lucia de Paiva; Alves, Ronaldo Fernandes Santos; Faccini, Lavinia Schuler (2022) [Artigo de periódico]
      Objective: Prenatal infection with the Zika virus (ZIKV) can lead to congenital Zika syndrome (CZS), characterized by microcephaly and brain injury. However, there are questions regarding the prevalence of microcephaly/CZS ...

    • Neurological evaluation of microcephalic children with Zika syndrome and congenital cytomegalovirus infection 

      Faccini, Lavinia Schuler; Friedrich, Luciana; Moura, Sara Kvitko de; Santa Maria, Fernanda Diffini; Bone, Steice da Silva Inácio de (2022) [Artigo de periódico]
      Introduction: The association between the virus prenatal infection by Zika virus (ZIKV) and central nervous system disorders has been well established and it has been described as the Congenital Syndrome Associated to the ...

    • Population-based surveillance for congenital zika virus syndrome: a latent class analysis of recorded cases from 2015–2018 

      Paixão, Enny Santos da; Rodrigues, Laura Cunha; Costa, Maria da Conceição Nascimento; Carvalho-Sauer, Rita de Cassia Oliveira; Oliveira, Wanderson Kleber de; Cardim, Luciana Lobato; Faccini, Lavinia Schuler; Andrade, Roberto Fernandes Silva; Rodrigues, Moreno Magalhães de Souza; Brickley, Elizabeth B.; Veiga, Rafael Valente; Costa, Larissa Catharina; Carmo, Eduardo Hage; Smeeth, Liam; Barreto, Mauricio Lima; Teixeira, Maria Gloria (2022) [Artigo de periódico]
      Abstract Objective: This study aims to describe clinical fndings and determine the medium-term survival of congenital zika syndrome (CZS) suspected cases. Methods: A retrospective cohort study using routine register-based ...

    • Possible emergence of Zika virus of African lineage in Brazil and the risk for new outbreaks 

      Matos, Sophia Martins Simon de; Hennigen, André Ferreira; Wachholz, Gabriela Elis; Rengel, Bruna Duarte; Faccini, Lavinia Schuler; Roehe, Paulo Michel; Varela, Ana Paula Muterle; Fraga, Lucas Rosa (2021) [Artigo de periódico]

    • Teratogens : a public health issue - a brazilian overview 

      Nascimento, Thiago Mazzu; Melo, Débora Gusmão; Morbioli, Giorgio Gianini; Carrilho, Emanuel; Vianna, Fernanda Sales Luiz; Silva, André Anjos da; Faccini, Lavinia Schuler (2017) [Artigo de periódico]
      Congenital anomalies are already the second cause of infant mortality in Brazil, as in many other middle-income countries in Latin America. Birth defects are a result of both genetic and environmental factors, but a ...

    • The age of brain organoids : tailoring cell identity and functionality for normal brain development and disease modeling 

      Porciuncula, Lisiane de Oliveira; Goto Silva, Lívia; Ledur, Pítia Flores; Rehen, Stevens Kastrup (2021) [Artigo de periódico]
      Over the past years, brain development has been investigated in rodent models, which were particularly relevant to establish the role of specific genes in this process. However, the cytoarchitectonic features, which determine ...

    • Zika Brazilian Cohorts (ZBC) Consortium: protocol for an individual participant data meta-analysis of congenital Zika syndrome after maternal exposure during pregnancy 

      Alecrim, Maria das Graças Costa; Ximenes, Ricardo Arraes de Alencar; Faccini, Lavinia Schuler; Zara, Ana Laura de Sene Amâncio (2021) [Artigo de periódico]
      Despite great advances in our knowledge of the consequences of Zika virus to human health, many questions remain unanswered, and results are often inconsistent. The small sample size of individual studies has limited ...

    • Zika virus envelope domain III recombinant protein delivered with saponin-based nanoadjuvant from Quillaja brasiliensis enhances anti-zika immune responses, including neutralizing antibodies and splenocyte proliferation 

      Cibulski, Samuel Paulo; Varela, Ana Paula Muterle; Teixeira, Thais Fumaco; Cancela, Martín; Sesterheim, Patrícia; Souza, Diogo Onofre Gomes de; Roehe, Paulo Michel; Silveira, Fernando (2021) [Artigo de periódico]
      Nanoadjuvants that combine immunostimulatory properties and delivery systems reportedly bestow major improvements on the efficacy of recombinant, protein-based vaccines. Among these, self-assembled micellar formulations ...