• Antimicrobial and toxicity evaluation of imidazolium-based dicationic ionic liquids with dicarboxylate anions 

      Kuhn, Bruna Luiza; Kaminski, Taís Fernanda Andrzejewski; Carvalho, Anderson Ramos; Fuentefria, Alexandre Meneghello; Johann, Bianca de Medeiros Barlett da Costa; Silva, Edilma Elayne da; Silveira, Gustavo Pozza; Silveira, Tássia Limana da; Soares, Felix Alexandre Antunes; Frizzo, Clarissa Piccinin (2021) [Artigo de periódico]
      Imidazolium-based dicationic ILs (DILs) presenting antimicrobial activity and relatively low toxicity are highly desirable and are envisioned for use in live tissue to prevent bacterial or fungal infections. In this ...
    • Healing and cytotoxic effects of Psidium guajava (Myrtaceae) leaf extracts 

      Fernandes, Kristianne Porta Santos; Bussadori, Sandra Kalil; Marques, Márcia Martins; Wadt, Nilsa Sumie Yamashita; Bach, Erna; Martins, Manoela Domingues (2010) [Artigo de periódico]
      Aim: The aims of this study were to evaluate the wound healing potential in vivo and the cytotoxic effects in vitro of Psidium guajava (Myrtaceae) leaf extract and commonly used corticosteroids. Methods: The healing effect ...
    • Synthesis and antiplasmodial activity of betulinic acid and ursolic acid analogues 

      Innocente, Adrine Maria; Silva, Gloria Narjara Santos da; Cruz, Laura Nogueira; Moraes, Miriam Santos de; Nakabashi, Myna; Sonnet, Pascal; Gosmann, Grace; Garcia, Célia Regina da Silva; Gnoatto, Simone Cristina Baggio (2012) [Artigo de periódico]
      More than 40% of the World population is at risk of contracting malaria, which affects primarily poor populations in tropical and subtropical areas. Antimalarial pharmacotherapy has utilised plant-derived products such as ...
    • Triterpene derivatives as relevant scaffold for new antibiofilm drugs 

      Silva, Gloria Narjara Santos da; Barros, Muriel Primon de; Macedo, Alexandre José; Gnoatto, Simone Cristina Baggio (2019) [Artigo de periódico]
      New medicines for the treatment of bacterial biofilm formation are required. For this reason, this study shows the in vitro activity of betulinic acid (BA), ursolic acid (UA) and their twenty derivatives against planktonic ...