Chemical composition of essential oils of piper jacquemontianum and piper variabile from Guatemala and bioactivity of the dichloromethane and methanol extracts
dc.contributor.author | Cruz, Sully M. | pt_BR |
dc.contributor.author | Cáceres, Armando | pt_BR |
dc.contributor.author | Alvarez, Luis | pt_BR |
dc.contributor.author | Morales, Julio | pt_BR |
dc.contributor.author | Apel, Miriam Anders | pt_BR |
dc.contributor.author | Henriques, Amelia Teresinha | pt_BR |
dc.contributor.author | Salamanca, Efraín | pt_BR |
dc.contributor.author | Giménez, Alberto | pt_BR |
dc.contributor.author | Vasquez, Yelkaira | pt_BR |
dc.contributor.author | Gupta, Mahabir P. | pt_BR |
dc.date.accessioned | 2011-11-11T01:19:19Z | pt_BR |
dc.date.issued | 2011 | pt_BR |
dc.identifier.issn | 0102-695X | pt_BR |
dc.identifier.uri | http://hdl.handle.net/10183/34298 | pt_BR |
dc.description.abstract | The essential oils from two native species from Guatemala were studied for their chemical composition and the dichloromethane and methanol extracts for their biological activity. A GC-MS analysis of the essential oil from Piper jacquemontianum Kunth, Piperaceae, showed 34 constituents, consisting mainly of linalool (69.4%), while Piper variabile C. DC. essential oil had 36 constituents, camphor (28.4%), camphene (16.6%) and limonene (13.9%) being the major components. Dichloromethane extracts of both species were cytotoxic against MCF-7, H-460 and SF-268 cell lines (<7 μg/mL). Dichloromethane extract of P. jacquemontianum was slightly active against bacteria (0.5 mg/mL), was active against promastigotes of Leishmania (20.4-61.0 μg/mL), and epimastigotes of Trypanosoma cruzi (51.9 μg/mL). The methanol extract of P. variabile showed antimalarial activity against Plasmodium falciparum F32 (4.5 μg/mL), and the dichloromethane extract against Leishmania (55.8-76.3 μg/mL) and T. cruzi (45.8 μg/mL). None of the extracts from the two species was active against Aedes aegypti larvae and Artemia salina nauplii. | en |
dc.format.mimetype | application/pdf | pt_BR |
dc.language.iso | eng | pt_BR |
dc.relation.ispartof | Revista brasileira de farmacognosia. São Paulo, SP. Vol. 21, n. 4 (Jul./Ago. 2011), p. 587-593 | pt_BR |
dc.rights | Open Access | en |
dc.subject | Piperaceae | pt_BR |
dc.subject | Antimicrobial activity | en |
dc.subject | Cytotoxic activity | en |
dc.subject | Óleos essenciais | pt_BR |
dc.subject | Essential oil | en |
dc.subject | Piper jacquemontianum | pt_BR |
dc.subject | Extracts | en |
dc.subject | Piper variabile | pt_BR |
dc.subject | Guatemala | en |
dc.subject | Piper | en |
dc.title | Chemical composition of essential oils of piper jacquemontianum and piper variabile from Guatemala and bioactivity of the dichloromethane and methanol extracts | pt_BR |
dc.type | Artigo de periódico | pt_BR |
dc.identifier.nrb | 000787643 | pt_BR |
dc.type.origin | Nacional | pt_BR |
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