Navegação Produção Científica por Autor "Ruiz-Linares, Andres"
Resultados 1-18 de 18
-
Amerind ancestry, socioeconomic status and the genetics of type 2 Diabetes in a Colombian population
(2012) [Artigo de periódico]The ‘‘thrifty genotype’’ hypothesis proposes that the high prevalence of type 2 diabetes (T2D) in Native Americans and admixed Latin Americans has a genetic basis and reflects an evolutionary adaptation to a past low ... -
Automatic landmarking identifies new loci associated with face morphology and implicates Neanderthal introgression in human nasal shape
(2022) [Artigo de periódico]We report a genome-wide association study of facial features in >6000 Latin Americans based on automatic landmarking of 2D portraits and testing for association with inter-landmark distances. We detected significant ... -
Dental size variation in admixed Latin Americans: effects of age, sex and genomic ancestry
(2023) [Artigo de periódico]Dental size variation in modern humans has been assessed from regional to worldwide scales, especially under microevolutionary and forensic contexts. Despite this, populations of mixed continental ancestry such as contemporary ... -
Developmental pathways inferred from modularity, morphological integration and fluctuating asymmetry patterns in the human face
(2018) [Artigo de periódico]Facial asymmetries are usually measured and interpreted as proxies to developmental noise. However, analyses focused on its developmental and genetic architecture are scarce. To advance on this topic, studies based on a ... -
Distribuições de dois SNPs do cromossoma Y em duas tribos sul-americanas (ache e guarani)
(1999) [Resumo publicado em evento] -
Evolutionary responses to a constructed niche: ancient mesoamericans as a model of gene-culture coevolution
(2012) [Artigo de periódico]Culture and genetics rely on two distinct but not isolated transmission systems. Cultural processes may change the human selective environment and thereby affect which individuals survive and reproduce. Here, we evaluated ... -
Facial asymmetry and genetic ancestry in Latin American admixed populations
(2015) [Artigo de periódico]Fluctuating and directional asymmetry are aspects of morphological variation widely used to infer environmental and genetic factors affecting facial phenotypes. However, the genetic basis and environmental determinants of ... -
Genetic variation and population structure in native americans
(2008) [Artigo de periódico]We examined genetic diversity and population structure in the American landmass using 678 autosomal microsatellite markers genotyped in 422 individuals representing 24 Native American populations sampled from North, Central, ... -
A genome-wide association scan implicates DCHS2, RUNX2, GLI3, PAX1 and EDAR in human facial variation
(2016) [Artigo de periódico]We report a genome-wide association scan for facial features in B6,000 Latin Americans. We evaluated 14 traits on an ordinal scale and found significant association (P valueso5 10 8) at single-nucleotide polymorphisms ... -
Geografía génica de Chile. Distribución regional de los aportes genéticos americanos, europeos y africanos
(2014) [Artigo de periódico]Background: The geographical distribution of genes plays a key role in genetic epidemiology. The Chilean population has three major stem groups (Native American, European and African). Aim: To estimate the regional rate ... -
Geographic patterns of genome admixture in Latin American mestizos
(2008) [Artigo de periódico]The large and diverse population of Latin America is potentially a powerful resource for elucidating the genetic basis of complex traits through admixture mapping. However, no genome-wide characterization of admixture ... -
Implications of the admixture process in skin color molecular assessment
(2014) [Artigo de periódico]The understanding of the complex genotype-phenotype architecture of human pigmentation has clear implications for the evolutionary history of humans, as well as for medical and forensic practices. Although dozens of genes ... -
Ribeiro's typology, genomes, and Spanish colonialism, as viewed from Gran Canaria and Colombia
(2004) [Artigo de periódico]Four biallelic and six multiallelic Y-chromosome polymorphisms were investigated in 59 Gran Canarian, 60 North African Berber and 46 Spanish subjects. These new data were merged with equivalent literature information to ... -
Socioeconomic status is not related with facial fluctuating asymmetry : evidence from latin-american populations
(2017) [Artigo de periódico]The expression of facial asymmetries has been recurrently related with poverty and/or disadvantaged socioeconomic status. Departing from the developmental instability theory, previous approaches attempted to test the ... -
Subtypes of Native American ancestry and leading causes of death: Mapuche ancestry-specific associations with gallbladder cancer risk in Chile
(2017) [Artigo de periódico]Latin Americans are highly heterogeneous regarding the type of Native American ancestry. Consideration of specific associations with common diseases may lead to substantial advances in unraveling of disease etiology and ... -
The impact of socioeconomic and phenotypic traits on self-perception of ethnicity in Latin America
(2021) [Artigo de periódico]Self-perception of ethnicity is a complex social trait shaped by both, biological and non-biological factors. We developed a comprehensive analysis of ethnic self-perception (ESP) on a large sample of Latin American mestizos ... -
Y-chromosome biallelic polymorphisms and native american population structure
(2002) [Artigo de periódico]It has been proposed that women had a higher migration rate than men throughout human evolutionary history. However, in a recent study of South American natives using mtDNA restriction fragment polymorphisms and Y-chromosome ...
