• Association between tumor-infiltrating limphocytes and sentinel lymph node positivity in thin melanoma 

      Santos, Fernando de Marco dos; Silva, Felipe Correa da; Pedron, Julia; Furian, Roque; Fortes, Cristina Deppermann; Bonamigo, Renan Rangel (2019) [Artigo de periódico]
      Abstract: Background: Sentinel lymph node biopsy in thin invasive primary cutaneous melanoma (up to 1mm thick) is a controversial subject. The presence of tumor-infiltrating lymphocytes could be a factor to be considered ...
    • Developing the pneumonia-optimized ratio for community-acquired pneumonia : an easy, inexpensive and accurate prognostic biomarker 

      Cury, Vinicius Ferraz; Antoniazzi, Lucas Quadros; Oliveira, Paulo Henrique Kranz de; Borelli, Wyllians José Vendramini; Cunha, Sainan Voss da; Frison, Guilherme Cristianetti; Moretto, Enrico Emerim; Seligman, Renato (2021) [Artigo de periódico]
      Introduction: Community-acquired pneumonia (CAP) is still a major public health problem. Prognostic scores at admission in tertiary services may improve early identification of severity and better allocation of resources, ...
    • Effect of uncaria tomentosa extract on purinergic enzyme activities in lymphocytes of rats submitted to experimental adjuvant arthritis model 

      Castilhos, Lívia Gelain; Rezer, João Felipe Peres; Ruchel, Gerônimo; Thorstenberg, Maria Luiza Prates; Jaques, Jeandre Augusto dos Santos; Braun, Josiane Bizzi Schlemmer; Doleski, Pedro Henrique; Rossato, Mateus Fortes; Silva, Mariane Arnoldi da; Casali, Emerson Andre; Cruz, Ritiel Corrêa da; Ferreira, Juliano; Athayde, Margareth Linde; Gonçalves, Jamile Fabbrin; Leal, Daniela Bitencourt Rosa (2015) [Artigo de periódico]
      Background: Considering that adjuvant arthritis is an experimental model of arthritis widely used for preclinical testing of numerous anti-arthritic agents, which were taken by a large number of patients worldwide, it is ...
    • Metabolic fate of glutamine in lymphocytes, macrophages and neutrophils 

      Curi, Rui; Newsholme, Philip; Curi, Tania Cristina Pithon; Melo, Mariza Pires de; Garcia, C.; Bittencourt Junior, Paulo Ivo Homem de; Guimarães, A. R. P (1999) [Artigo de periódico]
      Eric Newsholme’s laboratory was the first to show glutamine utilization by lymphocytes and macrophages. Recently, we have found that neutrophils also utilize glutamine. This amino acid has been shown to play a role in ...
    • Mortality of septic shock patients is associated with impaired mitochondrial oxidative coupling efficiency in lymphocytes : a prospective cohort study 

      Nedel, Wagner Luís; Carvalho, Afonso Kopczynski de; Rodolphi, Marcelo Salimen; Strogulski, Nathan Ryzewski; De Bastiani, Marco Antônio; Montes, Tiago Hermes Maeso; Abruzzi Junior, Jose; Galina, Antônio; Horvath, Tamas L.; Portela, Luis Valmor Cruz (2021) [Artigo de periódico]
      Background: Septic shock is a life-threatening condition that challenges immune cells to reprogram their mitochondrial metabolism towards to increase ATP synthesis for building an appropriate immunity. This could print ...