Navegação Ciências da Saúde por Título
Resultados 6229-6248 de 10550
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Long-term follow-up of kidney allografts in patients with sickle cell hemoglobinopathy
(2003) [Artigo de periódico]Embora a anemia falciforme e as síndromes falciformes freqüentemente causem várias alterações funcionais renais, não é comum a insuficiência renal terminal. Nestes casos, o transplante renal é uma alternativa que se acompanha ... -
Long-term follow-up of renal function in patients treated with migalastat for Fabry disease
(2021) [Artigo de periódico]The effect of migalastat on long-term renal outcomes in enzyme replacement therapy (ERT)–naive and ERTexperienced patients with Fabry disease is not well defined. An integrated posthoc analysis of the phase 3 clinical ... -
Long-term galsufase treatment associated with improved survival of patients with mucopolysaccharidosis VI (Maroteaux-Lamy Syndrome) : 15-year follow-up from the survey study
(2018) [Artigo de periódico]Mucopolysaccharidosis VI (MPS VI) is a progressive lysosomal storage disorder with multiorgan and multisystemic pathology. Currently, galsulfase enzyme replacement therapy (ERT) is the only approved treatment for MPS VI. ... -
Long-term outcomes of systemic therapies for Hurler syndrome : an international multicenter comparison
(2018) [Artigo de periódico]Purpose: Early treatment is critical for mucopolysaccharidosis type I (MPS I), justifying its incorporation into newborn screening. Enzyme replacement therapy (ERT) treats MPS I, yet presumptions that ERT cannot penetrate ... -
Long-term outcomes with agalsidase alfa enzyme replacement therapy : analysis using deconstructed composite events
(2017) [Artigo de periódico]This is a retrospective analysis of Fabry Outcome Survey data from children/adults (n =677) receiving agalsidase alfa enzyme replacement therapy for a median of 3 years, examining cerebrovascular, cardiac, and renal morbidity ... -
Long-term reestablishment of alpha-L-iduronidase activity in MPS I fibroblasts after non-viral gene transfer
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Long-term risk factors for old-age social exclusion in Sweden : a 30-year longitudinal study
(2022) [Artigo de periódico]Purpose of the research: Social exclusion threatens quality of life in older age. However, there is a lack of research on social exclusion from life-course and gender perspectives. We investigated early- and midlife risk ... -
Long-term safety and clinical outcomes of olipudase alfa enzyme replacement therapy in pediatric patients with acid sphingomyelinase deficiency : two-year results
(2022) [Artigo de periódico]Background Acid sphingomyelinase deficiency (ASMD) is a lysosomal disorder caused by deficiency of acid sphingomyelinase (ASM) leading to the accumulation of sphingomyelin (SM) in a variety of cell types. Lysosphingomyelin ... -
Long-term sequelae of TB and COVID-19 co-infection : prospective cohort evaluation after 1 year
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Long-term treatment with clozapine and verbal memory performance in schizophrenia
(2018) [Artigo de periódico]Clozapine is more efficacious than first-generation antipsychotics for positive and negative symptoms, although it is related with serious adverse effects. Because of this profile, it could also have an impact on cognition. ... -
Los materiales curriculares impresos en educación física clasificación, usos e investigación
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Low birth weight in São Luís, northeastern Brazil : trends and associated factors
(2014) [Artigo de periódico]Background: To analyze trends in LBW (low birth weight) rate using birth registry data and identify factors associated with LBW in São Luís comparing two birth cohorts separated by a 12-year interval. Methods: 2,426 births ... -
Low concordance between NYHA classification and cardiopulmonary exercise test variables in patients with heart failure and reduced ejection fraction
(2022) [Artigo de periódico]Background: The New York Heart Association (NYHA) functional classification is the most commonly used classification system for heart failure (HF), whereas cardiopulmonary exercise testing (CPET) is the gold standard for ... -
Low-density lipoprotein values estimated by Friedewald equation are affected by diabetes control
(2016) [Artigo de periódico]Background: Friedewald equation (FE) is widely used to estimate the LDL-c without the use of ultra-centrifugation. However, the equation has limitations in some clinical settings. Objective: Our goal was to investigate the ... -
Low-dose adrenocorticotropin test in patients with the acquired immunodeficiency
(2001) [Artigo de periódico]Adrenocortical insufficiency is a serious complication of AIDS. Usually, integrity of the hypothalamo-pituitary-adrenal (HPA) axis in AIDS patients is assessed by measuring basal cortisol levels and cortisol response to ... -
Low-dose aspirin does not affect the renal function of microalbuminuric type 2 diabetic patients
(2011) [Artigo de periódico]Background: low-grade inflammation has been implicated in the pathogenesis of diabetic nephropathy, and anti-inflammatory drugs could be potentially useful as a therapeutic tool. The aim of this study was to analyze the ... -
Lower limb force, power and performance in skateboarding : an exploratory study
(2012) [Artigo de periódico]The purpose of this study was to identify the relationship between the height reached when performing the Ollie maneuver and the muscle force and power of the lower limbs required by beginner level skateboarders. Ten ... -
Lower serum 25-hydroxyvitamin D levels are associated with impaired glomerular filtration rate in type 2 diabetes patients
(2020) [Artigo de periódico]Background: 25-Hydroxyvitamin D [25(OH)D] deficiency has been implicated as a possible risk factor for the onset and progression of diabetes kidney disease (DKD). The aim of this study was to evaluate the interaction between ... -
Low-frequency fatigue at maximal and submaximal muscle contractions
(2009) [Artigo de periódico]Skeletal muscle force production following repetitive contractions is preferentially reduced when muscle is evaluated with lowfrequency stimulation. This selective impairment in force generation is called low-frequency ...