Síntese em fase sólida convergente de derivados 5-amidos diidropirimidinonas
dc.contributor.advisor | Eifler-Lima, Vera Lucia | pt_BR |
dc.contributor.author | Siqueira, Felipe Segabinazzi | pt_BR |
dc.contributor.author | Crestani, Allan | pt_BR |
dc.contributor.author | Canto, Rômulo Faria Santos | pt_BR |
dc.date.accessioned | 2010-11-23T04:19:31Z | pt_BR |
dc.date.issued | 2010 | pt_BR |
dc.identifier.uri | http://hdl.handle.net/10183/26837 | pt_BR |
dc.description.abstract | Dihydropirimidinones (DHPMs) are molecules whose synthesis is known since 1893, and lately has been receiving increased attention due to its diversity of pharmacological actions, such as: anti-tumor activity, antiviral, antiinflammatory, calcium channel blocker and antiparasitic. In our study, we performed the synthesis of DHPM, its hydrolysis by conventional heating and microwave, and after that, was added amine in these DHPMs hydrolysed by solid-phase organic synthesis (SPOS). | en |
dc.format.mimetype | application/pdf | |
dc.language.iso | por | pt_BR |
dc.rights | Open Access | en |
dc.subject | Síntese orgânica em fase sólida | pt_BR |
dc.subject | Dihydropirimidinones | en |
dc.subject | Biginelli reaction | en |
dc.subject | Solid-phase organic synthesis | en |
dc.title | Síntese em fase sólida convergente de derivados 5-amidos diidropirimidinonas | pt_BR |
dc.type | Trabalho de conclusão de graduação | pt_BR |
dc.identifier.nrb | 000758698 | pt_BR |
dc.degree.grantor | Universidade Federal do Rio Grande do Sul | pt_BR |
dc.degree.department | Faculdade de Farmácia | pt_BR |
dc.degree.local | Porto Alegre, BR-RS | pt_BR |
dc.degree.date | 2010 | pt_BR |
dc.degree.graduation | Farmácia | pt_BR |
dc.degree.level | graduação | pt_BR |
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