Browsing Pharmacy - Undergraduate degree by Subject "Gene editing"
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Edição genética com CRISPR no contexto da fibrose cística : revisão integrativa
(2021) [Work completion of graduation]A fibrose cística (FC) é uma das doenças recessivas monogênicas mais estudadas. A doença pode ser tratada com tratamentos específicos, entretanto, o prognóstico ainda permanece muito ruim e limitado. A expectativa média ... -
Neonatal intravenous injection of CRISPR/Cas9 liposomal complex has no incidence of off-targets in mice
(2022) [Work completion of graduation]Gene therapy has been increasingly researched for the treatment of diseases and the CRISPR/Cas9 system is considered a highly advanced and specific tool. However, it is necessary to reduce the chances of off-target cleavage, ...